Prof WU, Shiu Sun Rudolf    胡紹燊 教授
Advisor (Environmental Science)
Department of Science and Environmental Studies
Contact
ORCiD
0000-0002-8865-8709
Phone
(852) 2948 8617
Email
rudolfwu@eduhk.hk
Address
10 Lo Ping Road, Tai Po, New Territories, Hong Kong
Website
https://pappl.eduhk.hk/rich/web/person.xhtml?pid=188703&name=WU, Shiu Sun Rudolf
Scopus ID
7402945079
Research Interests

1. Epigenetic and trans-generational effects induced by hypoxia and chemicals

2. Impact of environmental stresses (especially hypoxia) on marine ecosystem structure and function

      Teaching Interests

      1. Ecology 

      2. Environmental science

      3. Environmental impact assessment 

      4. Toxicology 

      External Appointments

      A.    International Appointments

        2009-now

        Director of the “Regional Centre of Excellence in Marine Pollution” of the Partnerships in Environmental Management  for the Seas of East Asia, United Nations.

        2014-2019       

        Member, National Working Group on Ecological Assessment and Management of China Coastline, China  

        2013                

        Commissioned by the International Atomic Energy Agency (IAEA) and PEMSEA of United Nations to conduct a 2 month attachment training for two IAEA fellows and two PEMSEA fellows in contaminant analysis and monitoring 

        2010                

        Invited by the International Atomic Energy Agency to conduct an international training workshop on “Biological and Chemical Monitoring”, Vienna, Austria

        2008-2015

        Appointed by the United Nations, as one of the 13 members of the “Group of Experts on Scientific Aspects of Marine  Environmental Protection” in the world.

        2006

        Appointed by the Natural Environment Research Council, UK, to serve as the external reviewer of the five year  strategic marine science programs in  the UK (a £100 million program)

        2006-2007       

        Member, Earth Sciences Panel, National Science Foundation, China

        2004-2008

        Member, Board of Directors, Society of Environmental Toxicology and Chemistry (SETAC) Asia Pacific

        2003-2014

        Appointed by the British government, to serve on the Scientific Advisory Panel, Environment Agency of the United  Kingdom

        2002-2004

        Appointed by the Intergovernmental Oceanographic Commission (IOC)/UNESCO, to serve as one of the 24 members in  the world on the Coastal Ocean Observations Panel

        2002-2010

        Appointed by United Nation Development Program / International Maritime Organization, to serve as a member of the  Multidisciplinary Expert Group

         

        B.     Hong Kong Government Appointments

           

          2017-2019       

          Member, Advisory Board for Feasibility Study of Identified Sites on the Periphery of Country Parks, Hong Kong Housing Authority

          2013-2016

          Steering committee member, Biodiversity Strategy and Action Plan, Hong Kong Government

          2013-2015

          Panel member, Innovation and Technology Commission, Hong Kong Government

          2006-2013

          Council member, Advisory Council on Food and Environmental Hygiene, Hong Kong Government

          2006-2010

          Council member, Research Grants Council, Hong Kong Government

          2006-2007

          Member, Earth Sciences Panel, National Science Foundation, China

          2005-2006

          Chairman, Biology Panel, Research Assessment Exercise, University Grants Committee, Hong Kong Government

          2002-2005

          Member, National Science Foundation of China / Research Grants Council of Hong Kong Joint Research scheme

          2001-2004

          Member, Harbor Area Treatment Scheme Monitoring Group, Hong Kong government

          2000-2004

          Chairman, Capture Fisheries Advisory Committee, Agriculture, Fisheries and Conservation Department, Hong Kong  government

          2000-2002

          Member, Aquaculture Advisory Committee, Agriculture, Fisheries and Conservation Department, Hong Kong  government

          2000-2001

          Appointed by the Hong Kong government as one of the six members of an International Review Panel, to review and  advise the development of the Strategic Sewage Disposal Scheme (a $27 billion project)

          1995-2001

          Member, Biology and Medicine Panel, Research Grants Council


           


          Personal Profile

          Professor Rudolf Wu received his PhD from the University of British Columbia. He joined the Education University as Research Chair Professor of the Department of Sciences and Environmental Studies in January 2016.  Prior to this appointment, he was the Chair Professor and Director of the School of Biological Sciences, the University of Hong Kong.  He was the Director of the “Centre for Marine Environmental Research and Innovative Technology”, an “Area of Excellence” (funded $66.5 million by the HK government and $31.8 million by the six collaborating Universities).  He is also the founding Director of the State Key Laboratory in Marine Pollution.   Currently, he is the Director of the “Regional Centre of Excellence in Marine Pollution” of the Partnerships in Environmental Management for the Seas of East Asia, United Nations.

          Professor Wu is ranked the top 1% scholar in his field (Essential Science Indicators). His research primarily focuses on the responses of marine animals and ecosystems to environmental stresses (especially hypoxia, xenobiotics and endocrine disrupting chemicals).  He has published one book, five book chapters, and over 250 papers in leading journals in environmental sciences, environmental toxicology and marine ecology. Professor Wu was the associated editor of five international journals, and also the Chief Guest Editor of seven special issues of the journal "Marine Pollution Bulletin".

          Professor Wu has served on numerous high level committees of the Hong Kong government (e.g. Chair of Research Assessment Panel, Chair of the Fisheries Advisory Committee, member of Research Grants Council and Advisory Council on Food and Environmental Hygiene) as well as expert/advisory groups of many international organizations (including the United Nations, the International Maritime organization, the Intergovernmental Oceanographic Commission, Food & Agriculture Organization and the Environment Agency of the United Kingdom).  He has been commissioned by the United Nations and International Atomic Energy Agency to conduct more than 30 international training workshops covering a wide spectrum of topics including environmental impact assessment, environmental risk management, food security and public health, marine ecosystem management, and environmental monitoring and control.

          Prof. Wu has secured over $140 million competitive research grants (as Principal Investigator), and completed numerous consultancy studies with a total contract value more than $40 million. Results and recommendations of many of his studies have formed the scientific basis and legal framework of environmental management in Hong Kong.

          Research Interests

          1. Epigenetic and trans-generational effects induced by hypoxia and chemicals

          2. Impact of environmental stresses (especially hypoxia) on marine ecosystem structure and function

              Teaching Interests

              1. Ecology 

              2. Environmental science

              3. Environmental impact assessment 

              4. Toxicology 

              External Appointments

              A.    International Appointments

                2009-now

                Director of the “Regional Centre of Excellence in Marine Pollution” of the Partnerships in Environmental Management  for the Seas of East Asia, United Nations.

                2014-2019       

                Member, National Working Group on Ecological Assessment and Management of China Coastline, China  

                2013                

                Commissioned by the International Atomic Energy Agency (IAEA) and PEMSEA of United Nations to conduct a 2 month attachment training for two IAEA fellows and two PEMSEA fellows in contaminant analysis and monitoring 

                2010                

                Invited by the International Atomic Energy Agency to conduct an international training workshop on “Biological and Chemical Monitoring”, Vienna, Austria

                2008-2015

                Appointed by the United Nations, as one of the 13 members of the “Group of Experts on Scientific Aspects of Marine  Environmental Protection” in the world.

                2006

                Appointed by the Natural Environment Research Council, UK, to serve as the external reviewer of the five year  strategic marine science programs in  the UK (a £100 million program)

                2006-2007       

                Member, Earth Sciences Panel, National Science Foundation, China

                2004-2008

                Member, Board of Directors, Society of Environmental Toxicology and Chemistry (SETAC) Asia Pacific

                2003-2014

                Appointed by the British government, to serve on the Scientific Advisory Panel, Environment Agency of the United  Kingdom

                2002-2004

                Appointed by the Intergovernmental Oceanographic Commission (IOC)/UNESCO, to serve as one of the 24 members in  the world on the Coastal Ocean Observations Panel

                2002-2010

                Appointed by United Nation Development Program / International Maritime Organization, to serve as a member of the  Multidisciplinary Expert Group

                 

                B.     Hong Kong Government Appointments

                   

                  2017-2019       

                  Member, Advisory Board for Feasibility Study of Identified Sites on the Periphery of Country Parks, Hong Kong Housing Authority

                  2013-2016

                  Steering committee member, Biodiversity Strategy and Action Plan, Hong Kong Government

                  2013-2015

                  Panel member, Innovation and Technology Commission, Hong Kong Government

                  2006-2013

                  Council member, Advisory Council on Food and Environmental Hygiene, Hong Kong Government

                  2006-2010

                  Council member, Research Grants Council, Hong Kong Government

                  2006-2007

                  Member, Earth Sciences Panel, National Science Foundation, China

                  2005-2006

                  Chairman, Biology Panel, Research Assessment Exercise, University Grants Committee, Hong Kong Government

                  2002-2005

                  Member, National Science Foundation of China / Research Grants Council of Hong Kong Joint Research scheme

                  2001-2004

                  Member, Harbor Area Treatment Scheme Monitoring Group, Hong Kong government

                  2000-2004

                  Chairman, Capture Fisheries Advisory Committee, Agriculture, Fisheries and Conservation Department, Hong Kong  government

                  2000-2002

                  Member, Aquaculture Advisory Committee, Agriculture, Fisheries and Conservation Department, Hong Kong  government

                  2000-2001

                  Appointed by the Hong Kong government as one of the six members of an International Review Panel, to review and  advise the development of the Strategic Sewage Disposal Scheme (a $27 billion project)

                  1995-2001

                  Member, Biology and Medicine Panel, Research Grants Council


                   


                  Research Outputs
                  Journal Publications
                  Publication in refereed journal
                  Yang, Y., Zhou, G.J., Li, Z.Y., Sun, J.J., Wong, A.S.T., Ko, V.C.C., WU, R.S.S., & Lai, K.P. (2024). Effects of Benzophenone-3 and Its Metabolites on the Marine Diatom Chaetoceros Neogracilis: Underlying Mechanisms and Environmental Implications. Science of The Total Environment, 923, 171371. https://doi.org/10.1016/j.scitotenv.2024.171371
                  Leung, R.K.L., Chui, A.P.Y., Liu, X.S., Lee, H.W., Leung, M.M.L., Wang, Y.J., Hu, M.H., Kwok, K.W.H., Wu, R.S.S., Jin, L., Kong, H.K., & Fang, J.F.,H. (2024). Bioaccumulation of Pollutants in the Green-lipped Mussel Perna Viridis: Assessing Pollution Abatement in Victoria Harbour and Its Adjacent Aquaculture Area, Hong Kong, and the Minimal Human Health Risks from Mussel Consumption. Marine Pollution Bulletin, 201, 116086. https://doi.org/10.1016/j.marpolbul.2024.116086
                  Kim, M.S., Lee, Y.H., Lee, Y.S., Byeong, E.J., Kim, D.H., Wang, M.H., Hagiwara, A., Aranda, M., Wu, R.S.S., Park, H.G., & Lee, J.S. (2024). Transgenerational Adaptation to Ocean Acidification Determines the Susceptibility of Filter-feeding Rotifers to Nanoplastic. Journal of Hazardous Materials, 461, 132593. https://doi.org/10.1016/j.jhazmat.2023.132593
                  Mallick, D., Kibria, G., Hossain, M.M.M., Lau, T.C., & Wu, R.S.S. (2024). A First Field Evaluation of Heavy Metals Uptake by Innovative Artificial Mussel (AM) Technology Versus Live Mussel (LM) from Inshore of the Bay of Bengal, Bangladesh and the Application of AM Technology for Global Pollution Study. Regional Studies in Marine Science, 69, 103337. https://doi.org/10.1016/j.rsma.2023.103337
                  Lee, Y., Byeon, E.J., Kim, D.H., Maszczyk, P., Wang, M.H., Wu, R.S.S., Jeung, H.D., Hwang, U.K., & Lee., J.S. (2023). Hypoxia in Aquatic Invertebrates: Occurrence and Phenotypic and Molecular Responses. Aquatic Toxicology, 263, 106685. https://doi.org/10.1016/j.aquatox.2023.106685
                  Yang, Y., Chow, T.W., Zhang, Y.Q., Yu, P.K.N., Ko, C.C., & Wu, R.S.S. (2023). Artificial Mussels: A New Tool for Monitoring Radionuclides in Aquatic Environments. Journal of Marine Science and Engineering, 11(7), 1309. https://doi.org/10.3390/jmse11071309
                  Qin, X., Lin, H., Cao, Y., Wu, R.S.S., Lai, K.P., & Kong, R.Y.C. (2023). Embryo Developmental Toxicity in Marine Medaka (Oryzias Melastigma) due to Parental and Embryonic 17α-ethinylestradiol Exposure. Science of the Total Environment, 861, 160594. https://doi.org/10.1016/j.scitotenv.2022.160594
                  Leung, C.T., Yang, Y., Chan, T.F., Lin, X., Wong, A.S.T., Liu, W.Y., Yuen, K.W.Y., Kong, R.Y.C., Lai, K.P., & Wu, R.S.S. (2023). Chromatin Modifiers: A New Class of Pollutants with Potential Epigenetic Effects Revealed by in Vitro Assays and Transcriptomic Analyses. Toxicology, 484, 153413. https://doi.org/10.1016/j.tox.2022.153413
                  Kibria, G., Stark, R., Nugegoda, D., & Wu, R.S.S. (2022). Replacing the Use of Live Mussels with Artificial Mussels to Monitor and Assess the Risks of Heavy Metals. Australasian Journal of Environmental Management, 30(1), 127-140. https://doi.org/10.1080/14486563.2022.2151521
                  Lai, K.P., Leung, C.C.T., Boncan, D.A.T., Tam, N., Lin, X., Wang, S.Y., Chan, T.F., Wu, R.S.S., & Kong, R.Y.C. (2022). Hypoxia-Induced Epigenetic Transgenerational miRNAs Dysregulation Involved in Reproductive Impairment of Ovary. Chemico-Biological Interactions, 367, 110176. https://doi.org/10.1016/j.cbi.2022.110176
                  Lee, Y.H., Kim, M.S., Wang, M., Bhandari, R.K., Park, H.G., Wu, R.S.S., & Lee, J.S. (2022). Epigenetic Plasticity Enables Copepods to Cope with Ocean Acidification. Nature Climate Change, 12, 918-927. https://doi.org/10.1038/s41558-022-01477-4
                  Qin, X., Lai, K.P., Wu, R.S.S., & Kong, R.Y.C. (2022). Continuous 17α-ethinylestradiol Exposure Impairs the Sperm Quality of Marine Medaka (Oryzias Melastigma). Marine Pollution Bulletin, 183, 114093. https://doi.org/10.1016/j.marpolbul.2022.114093
                  Leung, C.T., Yang, Y., Yu, K.N., Tam, N., Chan, T.F., Lin, X., Kong, R.Y.C., Chiu, J.M.Y., Wong, A.S.T., Lui, W.Y., Yuen, K.W.Y., Lai, K.P., & Wu, R.S.S. (2021). Low-Dose Radiation Can Cause Epigenetic Alterations Associated With Impairments in Both Male and Female Reproductive Cells (doi: https://doi.org/10.3389/fgene.2021.710143). Frontiers in Genetics, retrieved from https://www.frontiersin.org/articles/10.3389/fgene.2021.710143/full, 12, 710143.
                  Wu, R.S.S., Giesy, J.P., Richardson, B.J., & Leung, K.M.Y. (2021). Editorial: In Memory of Dr. Doris Au (29 April 1965–7 February 2020). Marine Pollution Bulletin, 167, 112278.
                  Lai, K.P., Tam, N., Wang, S.Y., Tse, W.K.F., Lin, X., Chan, T.F., Tong, Y., Zhang, J.W., Au, D.W.T., Wu, R.S.S., & Kong, R.Y.C. (2021). Proteomic Response of the Brain to Hypoxic Stress in Marine Medaka Fish (Oryzias melastigma) (doi: https://doi.org/10.3389/fmars.2021.618489). Frontiers in in Marine Science, retrieved from https://www.frontiersin.org/articles/10.3389/fmars.2021.618489/full, 8, 618489.
                  Sheppard, C., Elliott, M., Richardson, B., Richardson, P., Shin, P.K.S., & Wu, R.S.S. (2021). Editorial: Brian Morton, PhD, DSc, OBE, JP (1942–2021): Celebrating the Life of Our Most Prolific Contributor (doi:https://doi.org/10.1016/j.marpolbul.2021.112482). Marine Pollution Bulletin, retrieved https://www.sciencedirect.com/science/article/pii/S0025326X21005166?via%3Dihub, In Press, 112481.
                  Wu, R.S.S., Leung, S.F., Lee, S.Y., Leung, K.F., Shin, P.K.S., Chan, L., & Leung, K.M.Y. (2021). Editorial: Tearful at the falling of a star: In memory of Professor Brian Morton (10th August 1942 – 28th March 2021). Marine Pollution Bulletin, In Press, 112481.
                  Cholumpai, V., Kachanopas-Barnette, P., Tubmeka, S., & Wu, R.S.S. (2020). Contamination of Cadmium and Mercury along the East Coast of the Gulf of Thailand: A Comparative Study Using the Green Mussel (Perna viridis), Artificial Mussel, Water and Sediment. American Academic Scientific Research Journal for Engineering, Technology, and Sciences, 73(1), 61-75.
                  Lai, P.K., Tam, N., Wang, Y.S., Lin, X., Chan, T.F., Au, W.T.D., Wu, R.S.S., & Kong, T.C. (2020). Hypoxia Causes Sex-specific Hepatic Toxicity at the Transcriptome Level in Marine Medaka (Oryzias Melastigma). Aquatic Toxicology, 224, 105520.
                  Shen, H., Kiabria, G., Wu, R.S.S., Morrision, P., & Nugegoda, D. (2020). Spatial and Temporal Variations of Trace Metal Body Burdens of Live Mussels Mytilus Galloprovincialis and Field Validation of the Artificial Mussels in Australian Inshore Marine Environment. Chemosphere, 248, 126004.
                  Li, N., Ho, W.K., Wu, R.S.S., Tsang, E.P.K., Ying, G.-G., & Deng, W.-J. (2019). Ultra Violet Filters in the Urine of Preschool Children and Drinking Water. Environment International, 133, 105246.
                  Lee, B.-Y., Kim, M.-S Kim, Choi, B.-S., Nagano, A.J., Au, D.W.T., Wu, R.S.S., Takehana, Y., & Lee, J.-S. (2019). Construction of High-Resolution RAD-Seq Based Linkage Map, Anchoring Reference Genome, and QTL Mapping of the Sex Chromosome in the Marine Medaka Oryzias Melastigma. G3: Gens, Genomes, Genetics, 9(11), 3537-3545.
                  Li, N., Ho, W.-K., Wu, R.S.S., Ying, G.-G., Wang, Z., Jones, K., & Deng, W.-J. (2019). Organophosphate Flame Retardants and Bisphenol A in Children's Urine in Hong Kong: Has the Burden Been Underestimated?. Ecotoxicology and Environmental Safety, 183, 109502.
                  Lai, K.P., Wang, S.Y., Li, J.W., Tong, Y., Chan, T.F., Jin, N., Tse, A., Zhang, J.W., Wan, M.T., Tam, N., Au, D.W.T., Lee, B.-Y., Lee, J.-S., Wong, A.S.T., Kong, R.Y.C., Wu, R.S.S. (2019). Hypoxia Causes Transgenerational Impairment of Ovarian Development and Hatching Success in Fish. Environmental Science and Technology, 53(7), 3917-3928.
                  Ruiz-Fernándeza, A.C., Wu, R.S.S., Lau, T.-C., Pérez-Bernala, L.C., Sánchez-Cabezad, J.A., & Chiu, J.M.Y. (2018). A Comparative Study on Metal Contamination in Estero de Urias Lagoon, Gulf of California, Using Oysters, Mussels and Artificial Mussels: Implications on Pollution Monitoring and Public Health Risk. Environmental Pollution, 243 (A), 197-205.
                  Chiu, J.M.Y., Po, B.H.K., Degger, N., Tse A., Liu, W.-H., Zheng, G., Zhao, D.-M., Xu, D., Richardson, B., & WU, R.S.-S. (2018). Contamination and Risk Implications of Endocrine Disrupting Chemicals along the Coastline of China: A Systematic Study Using Mussels and Semipermeable Membrane Devices. Science of the Total Environment, 624, 1298-1307.
                  Genc, T.O., Po, B.H.K., Yılmaz, F., Lau, T.-C., Wu, R.S.S., & Chiu, J.M.Y. (2018). Differences in Metal Profiles Revealed by Native Mussels and Artificial Mussels in Sarıçay Stream, Turkey: Implications for Pollution Monitoring (doi: 10.1071/MF17293). Marine and Freshwater Research, Retrieved from http://www.publish.csiro.au/MF/MF17293, online, 1-7.
                  Lai, K.P., Li, J.W., Wang, S.Y., Wan, M.T., Chan, T.F., Liu, W.Y., Au, D.W.-T., WU, R.S.-S., & Kong, R.Y.-C. (2018). Transcriptomic Analysis Reveals Transgenerational Effect of Hypoxia on the Neural Control of Testicular Functions. Aquatic Toxicology, 195, 41-48.
                  Deng, Wen-Jing, Li Na, Wu Rudolf, Wong K.S. Richard , Wang Zijian, Ho Wingkei (2018). Phosphorus flame retardants and Bisphenol A in indoor dust and PM2.5 in kindergartens and primary schools in Hong Kong. Environmental Pollution, 235, 365-371.
                  Chen, W.-T., Lau, S.-W., Fan, Y.-Q., Wu, R.S.-S., & Ge, W. (2017). Juvenile Exposure to Bisphenol A Promotes Ovarian Differentiation But Suppresses Its Growth – Potential Involvement of Pituitary Follicle-Stimulating Hormone. Aquatic Toxicology, 193, 111-121.
                  Tan, T.-F., Yu, R.M.K., Wu, R.S.-S., & Kong, R.Y.C. (2017). Overexpression and Knockdown of Hypoxia-Inducible Factor 1 Disrupt the Expression of Steroidogenic Enzyme Genes and Early Embryonic Development in Zebrafish. Gene Regulation and Systems Biology, 11, 1-11.
                  Kibria, G., Hossain, M.M., Mallick, D., Lau, T.C., & Wu, R.S.S. (2016). Monitoring of Metal Pollution in Waterways across Bangladesh and Ecological and Public Health Implications of Pollution. Chemosphere, 165, 1-9.
                  Chiu, J.M.Y., Degger, N., Leung, J.Y.S., Po, B.H.K., Zheng, G.J., Richardson, B.J., Lau, T.C., & Wu, R.S.S. (2016). A Novel Approach for Estimating the Removal Efficiencies of Endocrine Disrupting Chemicals and Heavy Metals in Wastewater Treatment Processes. Marine Pollution Bulletin, 112(1), 53-57.
                  Tse, A.C.K., Li, J.W., Wang, S.Y., Chan, T.F., Lai, K.P., & Wu, R.S.S. (2016). Hypoxia Alters Testicular Functions of Marine Medaka through MicroRNAs Regulation. Aquatic Toxicology, 180, 266-273.
                  Degger, N., Chiu, J.M.Y., Po, B.H.K., Tse., A.C.K., Zheng, G.J., Zhao, D.M., Xu, D., Cheng, Y.S., Wang, X.H., Liu, W.H., Lau, T.C., & Wu, R.S.S. (2016). Heavy Metal Contamination along the China Coastline: A Comprehensive Study Using Artificial Mussels and Native Mussels. Journal of Environmental Management, 180, 238-246.
                  Tse, K.F.W., Li, J.W., Tse, A.C.K., Chan, T.F., Ho., J.C.H., Wu, R.S.S., Wong, C.K.C., & Lai, P.K. (2016). Fatty Liver Disease Induced by Perfluorooctane Sulfonate: Novel Insight from Transcriptome Analysis. Chemosphere, 159, 166-177.
                  Lai, K.P., Li, J.W., Tse, A.C.K., Cheung, A., Wang, S., Chan, T.F., Kong, R.Y.C., & Wu, R.S.S. (2016). Transcriptomic Responses of Marine Medaka's Ovary to Hypoxia. Aquatic Toxicology, 177, 476-483.
                  Wang, S.Y., Lau, K., Lai, K.P., Zhang, J.W., Tse, A.C.K., Li, J.W., Tong, Y., Chan, T.F., Wong, C.K.C., Chiu, J.M.Y., Au, D.W.T., Wong, A.S.T., Kong, R.Y.C., & Wu, R.S.S. (2016). Hypoxia Causes Transgenerational Impairments in Reproduction of Fish. Nature Communications, 7, 1-9.
                  Li, J.W., Lin, X., Tse, A., Cheung, A., Chan., T., Kong, R.Y.C., Lai, K.P., & Wu, R.S.S. (2016). Discovery and Functional Characterization of Novel miRNAs in the Marine Medaka Oryzias Melastigma. Aquatic Toxicology, 175, 106-116.
                  Kibria, G., Hossain, M. M., Mallick, D., Lau, T. C. K., & Wu, R. S. S. (2016). Trace/Heavy Metal Pollution Monitoring in Estuary and Coastal Area of Bay of Bengal, Bangladesh and Implicated Impacts. Marine Pollution Bulletin, 105(1), 393-402.
                  Lai, K.P., Li, J.W., Tse, A.C.K., Chan, T.F. & Wu, R.S.S. (2016). Hypoxia alters steroidogenesis in female marine medaka through miRNAs regulation. Aquatic Toxicology, 172, 1-8.
                  Lai, K.P., Li, J.W., Tse, A.C.K., Wang, S.Y., Chan, T.F. & Wu, R.S.S. (2016). Differential Responses of Female and Male Brains to Hypoxia in the Marine Medaka Oryzias Melastigma. Aquatic Toxicology, 172, 36-43.
                  Kim, B.M., Kim, J., Choi, I.Y., Raisuddin, S., Au, D.W.T., Leung, K.M.Y., Wu, R.S.S., Rhee, J.S. & Lee, J.S. (2016). Omics of the marine medaka (Oryzias melastigma) and its relevance to marine environmental research. Marine Environmental Research, 113, 141-152.


                  Projects
                  Radionuclide Monitoring using Artificial Mussels
                  Recently, we have successfully developed the Artificial Mussel as an effective tool for monitoring radionuclides in the aquatic environment, which overcomes the longstanding problem and difficulties of radionuclide monitoring in the natural environment. In collaboration with Seoul National University (South Korea) and Xiamen University (China), this collaborative project aimed to use this novel technology to monitor radionuclides wastewater discharged from Fukushima Japan in Korea and Chinese coastal waters.
                  Project Start Year: 2023, Principal Investigator(s): WU, Shiu Sun, Rudolf

                   
                  Epigenetic Adaptation to Climate Change
                  ...
                  Project Start Year: 2021, Principal Investigator(s): LEE, Jae-Seong (WU, Shiu Sun Rudolf 胡紹燊 as Co-Investigator)

                   
                  Transgenerational Effects of Epigenetic Modifiers
                  ..
                  Project Start Year: 2021, Principal Investigator(s): WU, Shiu Sun Rudolf 胡紹燊

                   
                  Addressing an Imminent Problem Presented by a New Class of Pollutants: Chemicals with Epigenetic and Transgenerational Effects
                  Using the marine medaka (Oryzias melastigma) as a fish model, this project will test the hypothesis that F0 exposed to environmental realistic concentration of some EDCs can cause epigenetic alterations associated with transgenerational reproductive impairment in both males and females in the subsequent generations (F1 to F3). Six EDCs commonly found in elevated concentrations in coastal waters of PRD and China [i.e. BDE-47, BPA, EE2, TBT, TDCPP and TCA) will be selected, and their transgenerational effects on reproductive fitness traits (including gametogenesis, fecundity, onset of puberty, fertilization success, sex ratio, sperm number and motility, ovarian atresia, hormonal changes and expression of related genes along the HPG axis, apoptosis and cell proliferation) will be studied. In parallel, high-throughput massively parallel sequencing will be used to reveal epigenetic changes (i.e. miRNA profile, global and gene specific DNA methylation patterns), to reveal the underlying mechanism underlying the observed reproductive.
                  Project Start Year: 2020, Principal Investigator(s): WU, Shiu Sun, Rudolf

                   
                  Development of a Suite of Novel in Vitro Assays for Screening of Epigenetic Modifiers
                  Using a testicular and an ovarian cell line, this project aims to develop a suite of novel in vitro bioassays to screen, identify and characterise EDCs with a high potency of epigenetic and transgenerational effects.
                  Project Start Year: 2019, Principal Investigator(s): WU, Shiu Sun Rudolf 胡紹燊

                   
                  Functional Responses of Marine Ecosystem to Hypoxia
                  State Key Laboratory in Marine Pollution Competitive Grants
                  Project Start Year: 2016, Principal Investigator(s): WU, Shiu Sun Rudolf 胡紹燊

                   
                  Unravelling the Epigenetic Mechanisms Underlying Reproductive Impairment Induced by Hypoxia
                  ..
                  Project Start Year: 2016, Principal Investigator(s): WU, Shiu Sun Rudolf 胡紹燊

                   
                  Global Artificial Mussel Watch
                  Earlier, we have developed a chemical device known as the “Artificial Mussel” (AM) which can provide a time-integrated estimate of metal concentrations in the environment. This has attracted international collaboration with Scotland, Iceland, Portugal, South Africa, Australia and South Korea. The overall results demonstrated that AM can provide a reliable time-integrated estimate of metal concentration over large biogeographic areas with very different hydrographic conditions, and overcome the shortcomings of monitoring metals in water, sediment and the use of biomonitors. Since 2016, we have further extended our collaboration to Bangladesh, the Philippines, Russia, Thailand, Norway, Mexico and Mainland China.
                  Project Start Year: 2016, Principal Investigator(s): WU, Shiu Sun Rudolf 胡紹燊, MURPHY, Mason, JACINTO, Gil S

                   
                  Trans-generational Effects of Hypoxia in Fish and Underlying Epigenetic Mechanisms
                  State Key Laboratory in Marine Pollution Competitive Grants
                  Project Start Year: 2014, Principal Investigator(s): WU, Shiu Sun Rudolf 胡紹燊

                   
                  Prizes and awards
                  Gold Medal
                  For project: "A New Generation of Dissolved Oxygen Sensor Using Replaceable Photo-sensing Film"
                  Date of receipt: /8/2022, Conferred by: International Invention Innovation Competition in Canada 2022
                   
                  Top 10 Best Invention Award
                  For project: "A New Generation of Dissolved Oxygen Sensor Using Replaceable Photo-sensing Film"
                  Date of receipt: /8/2022, Conferred by: International Invention Innovation Competition in Canada 2022
                   
                  Special Award
                  For project: "A New Generation of Dissolved Oxygen Sensor Using Replaceable Photo-sensing Film"
                  Date of receipt: /8/2022, Conferred by: International Invention Innovation Competition in Canada 2022
                   
                  Sliver Medal

                  Date of receipt: 28/3/2022, Conferred by: 2022 Special Edition – Inventions Geneva Evaluation Days
                   
                  Patents
                  Apparatus, System, Sensor and Method for Determining Dissolved Oxygen Content in a Medium
                  Apparatus, System, Sensor and Method for Determining Dissolved Oxygen Content in a Medium - A/B01
                   
                  Apparatus, System, Sensor and Method for Determining Dissolved Oxygen Content in a Medium
                  The present application relates to an apparatus, a system, a sensing device and a method for measuring dissolved oxygen in a medium. - A/B01
                   
                  Apparatus, System, Sensor and Method for Determining Dissolved Oxygen Content in a Medium
                  The present application relates to an apparatus, a system, a sensing device and a method for measuring dissolved oxygen in a medium. - A/B01