Prof CHAN, Che Hin Chetwyn    陳智軒 教授
Vice President (Research and Development)
Office of the Vice President (Research and Development)
Contact
ORCiD
0000-0003-0307-6337
Phone
(852) 2948 6322
Email
cchchan@eduhk.hk
Address
10 Lo Ping Road, Tai Po, New Territories, Hong Kong
Scopus ID
16244174500
Research Interests

Professor Chan’s research work focuses on exploring mechanisms underlying human learning particularly perceptual and cross-modal learning employing brain imaging, electroencephalogram, and behavioral methods. He also applies the mechanisms to understand the behaviors of people with disabilities and older individuals, and design interventions to enhance individuals’ functional capabilities. He published more than 200 research papers and secured more than $20 million competitive research and development grants. Professor Chan is chief specialty editor of Frontiers in Rehabilitation Science and associate editor of Journal of Sports and Health Science.

External Appointments

2020 - Present   Chief Editor, Translational Research in Rehabilitation Specialty, Frontiers in Rehabilitation Sciences

2020 – Present  Member, Employees Retraining Board, Hong Kong; member, Finance and Administration Committee, Employees Retraining Board, Hong Kong

2020 – Present  Convenor, Quality Assurance and Review Committee, Employees Retraining Board, Hong Kong

2019 - Present   International Advisor, Advisory Committee, University of Rehabilitation, China

2019 - Present   Member, Committee on Enhancing of Franchised Bus Safety, Transport Department, HKSAR Government

2018 – Present  Member, Medical Social Collaboration Liaison Meeting, Hong Kong Hospital Authority

2018 – Present  Chairman, Advisory Committee on Social Work Training and Manpower Planning, Labour and Welfare Bureau, HKSAR Government

2017 – Present  Member, Committee on Self-financing Post-secondary Education (CSPE), Education Bureau, HKSAR Government

2017 – Present  Member, Quality Assurance Council, University Grants Committee, Hong Kong

2016 – Present  Member, School Allocation Committee, Education Bureau, HKSAR Government

2015 – Present  Chair, Committee on Rehabilitation, The Hong Kong Society for Rehabilitation

2015 – Present  Vice-Chair, Executive Committee, The Hong Kong Society for Rehabilitation

2014 – Present  Member, Review Panel, Health and Medical Research Fund, Food and Health Bureau, HKSAR Government

2013 – Present  Member, Hospital Governing Committee, Princess Margaret Hospital and Kwai Chung

Hospital, Hong Kong Hospital Authority

2013 – Present  Associate Editor, Journal of Sport and Health Science

Personal Profile

Professor Chetwyn Chan is Vice President (Research and Development) and Chair Professor of Psychology. He obtained his Ph.D. in Educational Psychology in 1995 from the University of Alberta, Canada. He is Peter T. C. Lee Endowed Chair Professor of Psychology. Professor Chan has been an elected Fellow of the American Psychological Association since 2008 and Fellow of the Hong Kong Psychological Society since 2007. In 2008, in recognition of his contributions to psychology and rehabilitation sciences, Professor Chan received the Global Leadership in Rehabilitation Science Award from Virginia Commonwealth University in the United States. In 2011, he received the Alumni Honour Award from the University of Alberta to recognize his influence on research and education development in rehabilitation in Asia. In 2018, Professor Chan and his research team won the First Prize in Science and Technology from the Chinese Association of Rehabilitation Medicine on post-stroke cognitive assessment and intervention innovation. In 2019, his research team won the Second Class State Scientific and Technology Progress Award from the State Council of the People’s Republic of China to integrate Chinese medicine into innovative post-stroke rehabilitation.

Research Interests

Professor Chan’s research work focuses on exploring mechanisms underlying human learning particularly perceptual and cross-modal learning employing brain imaging, electroencephalogram, and behavioral methods. He also applies the mechanisms to understand the behaviors of people with disabilities and older individuals, and design interventions to enhance individuals’ functional capabilities. He published more than 200 research papers and secured more than $20 million competitive research and development grants. Professor Chan is chief specialty editor of Frontiers in Rehabilitation Science and associate editor of Journal of Sports and Health Science.

External Appointments

2020 - Present   Chief Editor, Translational Research in Rehabilitation Specialty, Frontiers in Rehabilitation Sciences

2020 – Present  Member, Employees Retraining Board, Hong Kong; member, Finance and Administration Committee, Employees Retraining Board, Hong Kong

2020 – Present  Convenor, Quality Assurance and Review Committee, Employees Retraining Board, Hong Kong

2019 - Present   International Advisor, Advisory Committee, University of Rehabilitation, China

2019 - Present   Member, Committee on Enhancing of Franchised Bus Safety, Transport Department, HKSAR Government

2018 – Present  Member, Medical Social Collaboration Liaison Meeting, Hong Kong Hospital Authority

2018 – Present  Chairman, Advisory Committee on Social Work Training and Manpower Planning, Labour and Welfare Bureau, HKSAR Government

2017 – Present  Member, Committee on Self-financing Post-secondary Education (CSPE), Education Bureau, HKSAR Government

2017 – Present  Member, Quality Assurance Council, University Grants Committee, Hong Kong

2016 – Present  Member, School Allocation Committee, Education Bureau, HKSAR Government

2015 – Present  Chair, Committee on Rehabilitation, The Hong Kong Society for Rehabilitation

2015 – Present  Vice-Chair, Executive Committee, The Hong Kong Society for Rehabilitation

2014 – Present  Member, Review Panel, Health and Medical Research Fund, Food and Health Bureau, HKSAR Government

2013 – Present  Member, Hospital Governing Committee, Princess Margaret Hospital and Kwai Chung

Hospital, Hong Kong Hospital Authority

2013 – Present  Associate Editor, Journal of Sport and Health Science

Research Outputs

Journal Publications
Publication in refereed journal
Wu, J., Song, J., He, Y., Li, Z., Deng, H., Huang, Z., Xie, X., Wong, N. M. L., Tao, J., Lee, T. M. C., & Chan, C. C. H. (2023). Effect of Tai Chi on young adults with subthreshold depression via a stress-reward comlex: A randomized controlled trial. Sports Medicine - Open, 9(1), 90-13. https://doi.org/10.1186/s40798-023-00637-w
Arleo, A., Bareš, M., Bernard, J. A., Bogoian, H. R., Bruchhage, M. M., Bryant, P., Carlson, E. S., Chan, C. C., Chen, L.-K., Chung, C.-P., Dotson, V. M., Filip, P., Guell, X., Habas, C., Jacobs, H. I. L., Kakei, S., Lee, T. M., Leggio, M., Misiura, M., . . . Manto, M. (2023). Consensus paper: Cerebellum and ageing. The Cerebellum. Advance online publication. https://doi.org/10.1007/s12311-023-01577-7
Law, C.-K., Kolling, N., Chan, C. C. H., & Chau, B. K. H. (2023). Frontopolar cortex represents complex features and decision value during choice between environments. Cell Reports, 42(6), 112555-112555. https://doi.org/10.1016/j.celrep.2023.112555
Wong, C. H. Y., Liu, J., Tao, J., Chen, L.‑D., Yuan, H.‑L., Wong, M. N. K., Xu, Y.0W., Lee, T. M. C., Chan, C. C. H. (2023). Causal influences of salience/cerebellar networks on dorsal attention network subserved age-related cognitive slowing. GeroScience. Advance online publication. doi: 10.1007/s11357-022-00686-1.
Wu, J., He, Y., Liang, S., Liu, Z., Hueng, J., Tao, J., Chen, L., Chan, C. H. C., Lee, T. M. C. (2023). Computerized cognitive training enhances episodic memory by down-modulating posterior cingulate-precuneus connectivity in older persons with mild cognitive impairment: A randomized controlled trial. American Journal of Geriatric Psychiatry, Advance online publication. doi: 10.1016/j.jagp.2023.04.008.
Wu, J., Tu, J., Liu, Z., Cao, L., He, Y., Huang, J., Tao, J., Wong, M., Chen, L., Lee, T. M. C., Chan, C. C. H. (2023). An Effective Test (EOmciSS) for Screening Older Adults with Mild Cognitive Impairment in a Community Setting: Development and Validation Study. Journal of Medical Internet Research, 25, e40858. DOI: 10.2196/40858.
Iwanaga, K., Chen, X., Wu, J., Lee, B., Deppert, B., Tansey, T., Chan, C., Tao, J. & Chan, F. (2022). Psychometric validation of the Wisconsin Community Participation Scale in a sample of people with chronic health conditions and disabilities living in the community. Rehabilitation Counseling Bulletin66(1), 58-65. http://doi.org/10.1177_00343552211063873
Hu, R., Lai, B., Ma, W., Zhang, Y., Deng, Y., Liu, L., Lv, Z., Chan, C., Zhang, F., &Tao, Q. (2022). How formal caregiver’s BPSD knowledge influences positive aspects of caregiving: the mediating role of attitude and the moderating role of self-efficiency. BMC Geriatrics, 22, 731. http://doi.org/10.1186/s12877-022-03417-5.
Hu, R., Zhang, F., Zhang, Y., Lai, B., Ma, W., Xu, X., Ye, H., Lv, Z., Chan, C., & Tao, Q. (2022) Development and validation of a Knowledge Scale about the Behavioral and Psychological Symptoms of Dementia (KS-BPSD) among Chinese formal caregivers. Clinical Gerontologist, 11, 1-9. doi: 10.1080/07317115.2022.2111290. Epub ahead of print. PMID: 35957605.
Yung, T. W. K., Lai, C. Y. Y., Chan, C. C. H. (2022). Abnormal physiological responses toward sensory stimulus are related to the attention deficits in children with sluggish cognitive tempo. Frontiers in Neuroscience, doi:10.3389/fnins.2022.875064.
Lei, L. K. S., Lam, B. Y. H., Lai, D. W. L., Bai, X., Li, J., Zou, Z., Chan, C. C. H. (2022). Stability of Montreal Cognitive Assessment in Individuals with Mild Cognitive Impairment: Potential Influence of Practice Effect. Journal of Alzheimer’s Disease, 87, 1401-1412. https://doi.org/10.3233/JAD-220003
Woo, T-F., Law, C-K., Ting, K-H., Chan, C. H. C., Kolling, N., Watanabe, K., & Chau, B. K. H. (2022). Distinct causal influences of dorsolateral prefrontal cortex and posterior parietal cortex in multiple-option decision making. Cerebral Cortex, 23(7), 1390-1404.
Derbie, A. Y., Chau, B. K. H., & Chan, C. C. H (2022). Functional and structural architectures of allocentric and egocentric spatial coding in aging: A combined DTI and fMRI study. Frontiers in Neurology, 12 https://doi.org/10.3389/fneur.2021.802975
Ahadullah, Yau, S.-Y., Lu, H.-X., Lee, T. M. C., Guo, H., & Chan, C. C. H. (2021). PM2.5 as a potential risk factor for autism spectrum disorder: Its possible link to neuroinflammation, oxidative stress and changes in gene expression. Neuroscience and Biobehavioral Reviews, 128, 534-548.
Bello, U. M., Chan, C. C. H., & Winser, S. J. (2021). Task complexity and image clarity facilitate motor and visuo-motor activities in mirror therapy in post-stroke patients. Frontiers in Neurology, 12, 1-13.
Hui, K. Y. L., Wong, C. H. Y., Siu, A. M. H., Lee, T. M. C., & Chan, C. C. H. (2021). Cognitive and emotional appraisal of motivational interviewing statements: An event-related potential study. Frontiers in Human Neuroscience, 15, 1-12.
Qi, D., Wong, N. M. L., Shao, R., Man, I. S. C., Wong, C. H. Y., Yuen, L. P., . . . Lee, T. M. C. (2021). Qigong exercise enhances cognitive functions in the elderly via an interleukin-6-hippocampus pathway: A randomized active-controlled trial. Brain, Behavior, and Immunity, 95, 381-390.
Yu, Q., Cheval, B., Becker, B., Herold, F., Chan, C. C. H., Delevoye-Turrell, Y. N., . . . Zou, L. (2021). Episodic memory encoding and retrieval in face-name paired paradigm: An fNIRS study. Brain Sciences, 11(7), 1-16.
Zhang, B. B. B., Kan, R. L. D., Woo, T.-F., Chan, C. C. H., Fong, K. N. K., & Kranz, G. S. (2021). Probing the effects of single-session iTBS on associative memory: A prospective, randomized, controlled cross-over study. Brain Stimulation, 14(4), 924-926.
Yung, T. W. K., Lai, C. Y. Y., Chan, J. Y. C., Ng, S. S. M., & Chan, C. C. H. (2021). Examining the role of attention deficits in the social problems and withdrawn behavior of children with sluggish cognitive tempo symptoms. Frontiers in Psychiatry, 12, 1-12.
Derbie, A. Y., Chau, B. K. H., Wong, C. H. Y., Chen, L.-D., Ting, K.-H., Lam, B. Y. H., . . . Chan, C. C. H. (2021). Common and distinct neural trends of allocentric and egocentric spatial coding: An ALE meta-analysis. European Journal of Neuroscience, 53(11), 3672-3687. https://doi.org/10.1111/ejn.15240
Wu, J., Tong, H., Liu, Z., Tao, J., Chen, L., Chan, C. C. H., & Lee, T. M. C. (2021). Neurobiological effects of perceived stress are different between adolescents and middle-aged adults. Brain Imaging and Behavior, 15, 846-854. https://doi.org/10.1007/s11682-020-00294-7
Chan, C. C. H. (2021). Grand Challenges of Translational Research in Rehabilitation. Frontiers in rehabilitation sciences, 2, 2021-03-24. https://www.frontiersin.org/article/10.3389/fresc.2021.625055
Chu, M. M. L., Chan, J., Chan, C. C. H. (2021). Predicting outcomes of conservative treatment for patients with carpal tunnel syndrome: Group- and individual-based rehabilitation. Hong Kong Journal of Occupational Therapy, 34(1), 39-49. https://doi.org/10.1177/1569186121997937
Wong, C. H. Y., Liu, J., Lee, T. M. C., Tao, J., Wong, A. W. K., Chau, B. K. H., Chen, L., & Chan, C. C. H (2021). Fronto-cerebellar connectivity mediating cognitive processing speed. NeuroImage, 226 https://doi.org/10.1016/j.neuroimage.2020.117556
Derbie, A. Y., Chau, B., Lam, B., Fang, Y-H., Ting, K-H., Wong, C. Y. H., . . . Chan, C. C. H. (2021). Cortical hemodynamic response associated with spatial coding: A near-infrared spectroscopy study. Brain Topography, 34, 207-220. https://doi.org/10.1007/s10548-021-00821-9
Gao, M., Wong, C. H. Y., Huang, H., Shao, R., Huang, R., Chan, C. C. H., & Lee, T. M. C. (2020). Connectome-based models can predict processing speed in older adults. NeuroImage, 223, 1-14.


Projects

Motor function impairments modulating neural connectivity: Implications to injured workers’ rehabilitation
This project is aimed to explore the impacts of upper limb dysfunctions on neural activities at the frontal, motor and parietal regions; and to design innovative interventions for enhancing the central- and peripheral-related functional recovery.
Project Start Year: 2021, Principal Investigator(s): CHAN, Che Hin Chetwyn 陳智軒

 
Probing homeostatic plasticity with priming theta-burst stimulation of the dorsolateral prefrontal cortex
This study is aimed to investigate the homeostatic plasticity of the dorsolateral prefrontal cortex by using transcranial magnetic stimulation; and explore the stimulation effects using the priming theta-burst protocol.
Project Start Year: 2021, Principal Investigator(s): Kranz, Georg (CHAN, Che Hin Chetwyn 陳智軒 as Co-Investigator)

 
Influence of the Gut-microbiota-brain Axis and Adiponectin on pro-cognitive functions of physical exercise
This study investigate how physical exercise can modulate the Gut-microbiota-brain Axis and Adiponectin by in an autism spectral disorder animal model.
Project Start Year: 2020, Principal Investigator(s): Yau, Sonata (CHAN, Che Hin Chetwyn 陳智軒 as Co-Investigator)

 
Maternal exposure to PM2.5 as a risk factor for developing autism-like behavior in offspring: the role of impaired hippocampal plasticity
This study is aimed to investigate the potential impacts of PM2.5 on the plasticity of the hippocampus and its relationships with developing autism-like behaviors in an animal model.
Project Start Year: 2020, Principal Investigator(s): Yau, Sonata (CHAN, Che Hin Chetwyn 陳智軒 as Co-Investigator)

 
Investigation of effect of maternal physical exercise on reversing chronic maternal exposure to PM2.5 - Induced autistic-like behavior in offspring
This study is aimed to investigate the effect of physical exercise on reversing the insults of offspring's brain functions by chronic maternal exposure to PM2.5 using an animal model.
Project Start Year: 2019, Principal Investigator(s): Yau, Sonata (CHAN, Che Hin Chetwyn 陳智軒 as Co-Investigator)

 
Tunable sonic perception control headset for children with Autism Spectrum Disorder
This study is aimed to detect auditory sensitivity with event-related potentials in children with autism spectral disorder; and to design a personalized noise-reduction algorithm and device for intervention.
Project Start Year: 2019, Principal Investigator(s): Choy, Tracy (CHAN, Che Hin Chetwyn 陳智軒 as Co-Investigator)